TY - BOOK AU - Werner, Haim TI - Insulin-Like Growth Factors in Development, Cancers and Aging SN - 9783040000000 KW - IGF-I||IGF-II||insulin||IGF-IR||IRs||tyrosine kinase receptor||GPCRs||hybrids||phosphorylation||G-proteins||β-arrestins||functional RTK/GPCR hybrid||nuclear translocation||IGF-I receptor||signaling||targeted therapeutics||IGF-Trap||IGF system||IGFBP-3||IGFBP-3R||TMEM219||anti-tumor||anti-metastatic||agonists||mAb therapy||IGF-1||IGFBP-1||older adults||longevity||health-span||age-related disease||cognitive impairment||diabetes||mitochondria||growth hormone||insulin-like growth factor-1||aging||oxidative stress||senescence||longitudinal study||IGFBP||mouse models||skeletal muscle||MSCs||myogenesis||glucose regulated protein (GRP) 94||insulin-like growth factor||obligate chaperone||hypertrophy||atrophy||cachexia||muscle regeneration||autophagy||IGF-1R||insulin receptor||IR-A||structural studies||receptor activation||n/a UR - https://mdpi.com/books/pdfview/book/3932 ER -