Aggregatibacter actinomycetemcomitans—Gram-Negative Bacterial Pathogen 

<br/><br/><br/>English[eng] 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aggregatibacter actinomycetemcomitans||cagE||virB1||virB4||genotype||virulence||mRNA assay||quantitative ELISA||cell lysis assay||leukotoxin||JP2 genotype||cytolethal distending toxin||lipopolysaccharides||cytokine binding factors||horizontal gene transfer||outer membrane vesicles||biofilm||proteomic||adherence||endocarditis||fimbriae||JP2||periodontitis||taxonomy||core and accessory genes||average nucleotide identity||principal component analysis||keratins||organotypic gingival mucosa||A. actinomycetemcomitans||RNA-Seq||genomic islands||core genes||accessory genes||stress||nutrient limitation||differentially expressed genes.||lymphocytes||apoptosis||RTX toxin||localized aggressive periodontitis||LFA-1||leukotoxin (LtxA)||endocytosis||n/a||JP2 clone of Aggregatibacter actinomycetemcomitans||JP2 in Caucasian||microbiological diagnosis||adjunctive antibiotics||localized aggressive periodontitis: animal studies: human studies||landscape ecology||damage/response framework||bacteremia||horseshoe crab||Origanum vulgare||essential oil||antimicrobial activity||minimum inhibitory concentration||minimal bactericidal concentration||cytotoxicity||leukotoxin neutralization||inflammasome||immune response||periodontal disease||proteomics